Author

Guillem Portella

University of CambridgeORCID 0000-0002-9380-6753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:experimental assay· 1 Organism:mouse· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Pierre MuratiD· 2 shared Shankar BalasubramanianiD· 2 shared Alba SalaiD· 1 shared Albert GandiosoiD· 1 shared Anna Maria AviñóiD· 1 shared Avazeh Tashakkori GhanbarianiD· 1 shared Barbara Herdy· 1 shared Carlos Gonzalez· 1 shared

Activity by Year

2017-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Pierre MuratORCID

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3 papers

Recent·Most cited

Molecular BiologyNucleic Acids ResearchPeer-reviewedFeb 27, 2025

Systematic study of hybrid triplex topology and stability suggests a general triplex-mediated regulatory mechanism

Vito Genna, Guillem Portella, Alba Sala…·Modesto Orozco

The paper systematically studies hybrid triplex topology and stability, revealing a regulatory mechanism in the human genome and transcriptome through triplex formation.

11 citations

humanDNA methylation

𝕏 PostBluesky

GenomicsbioRxivPreprintNov 24, 2017

5-Formylcytosine controls nucleosome positioning through covalent histone-DNA interaction

Eun‐Ang Raiber, Guillem Portella, Sergio Martínez Cuesta…·Shankar Balasubramanian

This study shows that 5-formylcytosine (5fC) influences nucleosome positioning through covalent histone-DNA interactions in mouse embryonic stem cells.

4 citations

mouseDNA methylation

𝕏 PostBluesky

GenomicsbioRxivPreprintNov 22, 2017

RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs

Pierre Murat, Giovanni Marsico, Barbara Herdy…·Shankar Balasubramanian

The paper identifies RNA G-quadruplexes in 5-UTRs as repressive elements that hinder translation by promoting upstream open reading frames, and shows helicases interact with these structures to regulate translation.

3 citations

humanRibo-seq

𝕏 PostBluesky