Author

Jianzhao Xu

Wake Forest University Health SciencesORCID 0000-0002-9105-819XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:electronic health records· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Anne B. NewmaniD· 2 shared Fang‐Chi HsuiD· 2 shared Ge LiiD· 2 shared Genesio Mugambi KarereiD· 2 shared Jeanne Chan· 2 shared Laura A. CoxiD· 2 shared Lauren Marie SparksiD· 2 shared Nancy E. LaneiD· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anne B. NewmanORCID

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3 papers

Recent·Most cited

MicroRNA regulatory targets of VO2peak in older adult participants of the Study of Muscle Mobility and Aging (SOMMA)

Genesio Mugambi Karere, Fang‐Chi Hsu, Russell T. Hepple, Paul M. Coen, Steve Cummings, Anne B. Newman, Nancy W. Glynn, Lauren Marie Sparks, Nancy E. Lane, Albert G. Hayward, Jianzhao Xu, Nathan Wagner, Ge Li, Jeanne Chan, Laura A. Cox, Stephen B. Kritchevsky

The paper identifies miRNA-gene regulatory networks associated with VO2peak in older adults using RNA sequencing and pathway analysis.

bioRxiv · Jan 22, 2026 · PreprintMolecular Biology

MicroRNA signatures of VO2peak in older adult participants of the Study of Muscle, Mobility and Aging

Genesio Mugambi Karere, Fang‐Chi Hsu, Russell T. Hepple, Paul M. Coen, Steve Cummings, Anne B. Newman, Nancy W. Glynn, Lauren Marie Sparks, Nancy E. Lane, Jianzhao Xu, Nathan Wagner, Ge Li, Jeanne Chan, Laura A. Cox, Stephen B. Kritchevsky

The paper identifies miRNA signatures associated with VO2peak variation in older adults using serum small RNA sequencing and statistical analysis.

The Journals of Gerontology Series A · Jul 18, 2025Peer-reviewedMolecular Biology

Progression of chronic kidney disease in African American with type 2 diabetes mellitus using topology learning in electronic medical records

Li Wang, Xufei Zheng, Lynn S. Huang, Jianzhao Xu, Fang‐Chi Hsu, Shyh‐Huei Chen, Maggie C.Y. Ng, Donald W. Bowden, Barry I. Freedman, Jing Su

This study uses EMRs and GWAS data to map CKD progression trajectories in African Americans with type 2 diabetes, identifying high-risk and low-risk pathways linked to APOL1 genotypes.

bioRxiv · Jul 4, 2018 · PreprintBioinformatics