Author

Russell T. Hepple

University of Florida HealthORCID 0000-0003-3640-486XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anne B. NewmaniD· 2 shared Fang‐Chi HsuiD· 2 shared Ge LiiD· 2 shared Genesio Mugambi KarereiD· 2 shared Jeanne Chan· 2 shared Jianzhao XuiD· 2 shared Laura A. CoxiD· 2 shared Lauren Marie SparksiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anne B. NewmanORCID

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3 papers

Recent·Most cited

PhysiologyThe Journal of PhysiologyPeer-reviewedSep 24, 2026

Mitochondrial Permeability Transition in Skeletal Muscle Phenocopies Muscle Alterations seen in Cancer Cachexia and other Wasting Conditions

Maya G. Semel, Cole J. Lukasiewicz, Sarah K. Skinner…·Russell T. Hepple

This study shows that inducing mitochondrial permeability transition (mPT) in skeletal muscle mimics key features of cancer cachexia and other wasting conditions, suggesting mPT as a potential therapeutic target.

DOI 10.1113/jp291213

mouseexperimental assay

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Molecular BiologybioRxivPreprintJan 22, 2026

MicroRNA regulatory targets of VO2peak in older adult participants of the Study of Muscle Mobility and Aging (SOMMA)

Genesio Mugambi Karere, Fang‐Chi Hsu, Russell T. Hepple…·Stephen B. Kritchevsky

The paper identifies miRNA-gene regulatory networks associated with VO2peak in older adults using RNA sequencing and pathway analysis.

1 citation

humanbulk RNA-seq

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Molecular BiologyThe Journals of Gerontology Series APeer-reviewedJul 18, 2025

MicroRNA signatures of VO2peak in older adult participants of the Study of Muscle, Mobility and Aging

Genesio Mugambi Karere, Fang‐Chi Hsu, Russell T. Hepple…·Stephen B. Kritchevsky

The paper identifies miRNA signatures associated with VO2peak variation in older adults using serum small RNA sequencing and statistical analysis.

DOI 10.1093/gerona/glaf159

humanbulk RNA-seq

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