Patricia Pestana Garcez

Zika virus oncolytic signaling reverts immunosuppressive and angiogenic glioblastoma microenvironment in vitro and in vivo

This study shows that Zika virus reprograms the glioblastoma tumor microenvironment to be anti-tumoral by inducing type III interferon signaling, which can be mimicked by exogenous treatment.

Zika virus infection during development impairs the formation of corpus callosum by disturbing axon guidance and growth of callosal neurons.

This study shows that Zika virus infection during development reduces callosal area and neuron density, disrupts axon guidance, and impairs corpus callosum formation in mice.

The cyanobacterial saxitoxin exacerbates neural cell death and brain malformations induced by Zika virus

This paper investigates whether saxitoxin from cyanobacteria worsens neural damage caused by Zika virus in Brazil, finding increased cell death and brain abnormalities in experimental models.