Luiza M. Higa

This study shows that Zika virus reprograms the glioblastoma tumor microenvironment to be anti-tumoral by inducing type III interferon signaling, which can be mimicked by exogenous treatment.

This study shows that Zika virus infection during development reduces callosal area and neuron density, disrupts axon guidance, and impairs corpus callosum formation in mice.

This study shows that ZIKV infection disrupts copper homeostasis in human astrocytes, leading to oxidative stress and cell death, and that copper chelation can reduce oxidative stress and improve cell viability.

This study shows Zika virus infection increases Aedes aegypti histone acetyltransferase CBP activity, enhancing immune gene expression and reducing viral titers.

This paper investigates whether saxitoxin from cyanobacteria worsens neural damage caused by Zika virus in Brazil, finding increased cell death and brain abnormalities in experimental models.