ImmunologybioRxivPreprint
A Novel 'Three-in-one' Mucosal Vaccine Elicits Broad Protection against Three Distinct Clusters of ACE2-using Sarbecoviruseses
Lin Liu, Haofeng Lin, Min Li…·Qingguo Wu
This paper develops a three-in-one mucosal vaccine, 3Rs-NC, that elicits broad neutralizing antibodies against three ACE2-using sarbecovirus clusters and provides durable protection in mice.
DOI 10.1101/2025.06.26.661659