Author

Megan K. Elder

New York UniversityORCID 0000-0002-9111-3152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Eric KlanniD· 2 shared Maggie Mamcarz· 2 shared Mauricio Martins OliveiraiD· 2 shared Ela N. GolhaniD· 1 shared Emily H. Lu· 1 shared Hediye Erdjument‐BromageiD· 1 shared Keylin Banegas-Morales· 1 shared Muhaned S. MohamediD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Eric KlannORCID

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2 papers

Recent·Most cited

The Integrated Stress Response effector GADD34 is repurposed by neurons to promote stimulus-induced translation

Mauricio Martins Oliveira, Muhaned S. Mohamed, Megan K. Elder, Keylin Banegas-Morales, Maggie Mamcarz, Emily H. Lu, Ela N. Golhan, Nishika Navrange, Snehajyoti Chatterjee, Ted G. Abel, Eric Klann

The paper shows that GADD34, an Integrated Stress Response effector, is used by neurons to enhance eIF2-dependent translation in response to BDNF stimulation.

Cell Reports · Jan 13, 2024Peer-reviewedNeuroscience

Dysregulation of the de novo proteome accompanies pathology progression in the APP/PS1 mouse model of Alzheimer's disease

Megan K. Elder, Hediye Erdjument‐Bromage, Mauricio Martins Oliveira, Maggie Mamcarz, Thomas A. Neubert, Eric Klann

The paper investigates early molecular changes in the APP/PS1 mouse model of Alzheimer's disease, finding dysregulation of the de novo proteome in synaptic, lysosomal, and mitochondrial pathways before pathology develops.

bioRxiv · Aug 21, 2020 · PreprintNeuroscience