Author

Emmanuel Ndashimye

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID 0000-0002-9112-9402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Christopher Warren· 1 shared Dai WangiD· 1 shared Daphne Ma· 1 shared Eberhard DürriD· 1 shared Eric J. ArtsiD· 1 shared Hannah O. AjogeiD· 1 shared Hinissan P. Kohio· 1 shared Jason S. McLellaniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Christopher Warren

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Author profile →

2 papers

Recent·Most cited

Structure-based design of soluble prefusion-stabilized herpes simplex virus type 2 glycoprotein B antigens

Madeline R. Sponholtz, Daphne Ma, Emmanuel Ndashimye, Patrick O. Byrne, Yi Shu, Christopher Warren, Nithya Thambi, Ryan S. McCool, Matthew D. Slein, Nicole V. Johnson, William A. Rose, Lan Zhang, Eberhard Dürr, Dai Wang, Jason S. McLellan

This study designs prefusion-stabilized HSV-2 gB antigens using structure-based methods and evaluates their immunogenicity, finding no improvement in neutralizing antibody titers compared to postfusion constructs.

Cell Reports · Sep 1, 2026Peer-reviewedMicrobiology

Specialized DNA structures act as genomic beacons for integration by evolutionarily diverse retroviruses.

Hinissan P. Kohio, Hannah O. Ajoge, Macon D. Coleman, Emmanuel Ndashimye, Richard M. Gibson, Eric J. Arts, Stephen Dominic Barr

This study identifies non-B DNA structures as genomic beacons for retroviral integration across diverse retroviruses, revealing subtype-specific preferences and shared hotspots.

Viruses · Feb 7, 2023Peer-reviewedMolecular Biology