Author

Aaron J. Goldman

Brigham and Women's HospitalORCID 0000-0002-9129-1311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Chunxiao CuiiD· 1 shared Danielle Hagee· 1 shared David S Goldman· 1 shared Ewa Beata GrassiniD· 1 shared Gabriel Gonzalez· 1 shared Himanshu ChintalapudiiD· 1 shared Hiroshi L. MashimoiD· 1 shared Leutz BuoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Chunxiao CuiORCID

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2 papers

Recent·Most cited

Glioblastoma Invasion Remodels Neural Circuits and Drives Persistent GABAergic Dysfunction in Human Brain Organoids

Ewa Beata Grassin, Himanshu Chintalapudi, Xianjun Dong, David S Goldman, Danielle Hagee, Chunxiao Cui, Aaron J. Goldman, Luke Lee

This study uses human brain organoids to show that glioblastoma invasion disrupts GABAergic neurons, causing persistent chloride imbalance and dysfunction, even after chemotherapy.

bioRxiv · Aug 12, 2026 · PreprintCancer Biology

Optimal Cannabinoid-Terpene Combination Ratios Suppress Mutagenicity of Gastric Reflux in Normal and Metaplastic Esophageal Cells

Aaron J. Goldman, Gabriel Gonzalez, Svetlana A. Karpova, Leutz Buon, Masood A. Shammas, Hiroshi L. Mashimo, Markus H. Frank, Natasha Y. Frank

The paper identifies an optimal cannabinoid-terpene ratio that reduces DCA-induced DNA damage and mutagenicity in esophageal cells and correlates ECS receptor expression with EAC progression.

World Journal of Gastroenterology · Apr 3, 2026Peer-reviewedCancer Biology