Author

Ewa Beata Grassin

Brigham and Women's HospitalORCID 0000-0002-9691-0417Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Himanshu ChintalapudiiD· 2 shared Xianjun DongiD· 2 shared Aaron J. GoldmaniD· 1 shared Chunxiao CuiiD· 1 shared Danielle Hagee· 1 shared David S Goldman· 1 shared Luke Lee· 1 shared Luke P. LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Himanshu ChintalapudiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 12, 2026

Glioblastoma Invasion Remodels Neural Circuits and Drives Persistent GABAergic Dysfunction in Human Brain Organoids

Ewa Beata Grassin, Himanshu Chintalapudi, Xianjun Dong…·Luke Lee

This study uses human brain organoids to show that glioblastoma invasion disrupts GABAergic neurons, causing persistent chloride imbalance and dysfunction, even after chemotherapy.

DOI 10.64898/2026.08.11.744022

humanscRNA-seq

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BioinformaticsbioRxivPreprintJun 24, 2025

EVscope: A Comprehensive Bioinformatics Pipeline for Accurate and Robust Analysis of Total RNA Sequencing from Extracellular Vesicles

Yiyong Zhao, Himanshu Chintalapudi, Ziqian Xu…·Xianjun Dong

EVscope is a bioinformatics pipeline for analyzing EV RNA-seq data, improving read assignment and contamination correction with a comprehensive annotation and visualization tool.

2 citations

bulk RNA-seqscRNA-seq

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