Author

Alessandra Aparecida Guarneri

Fiocruz MinasORCID 0000-0002-9162-2731Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Fabiano Sviatopolk-Mirsky PaisiD· 2 shared Antônio Edson Rocha OliveiraiD· 1 shared Ariel Mariano SilberiD· 1 shared Ashton T. BelewiD· 1 shared Bruna Mattioly Valente· 1 shared Fernanda L. B. MüggeiD· 1 shared Gabriel da Rocha FernandesiD· 1 shared Gabriela Torres MontanaroiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Fabiano Sviatopolk-Mirsky PaisORCID

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3 papers

Recent·Most cited

BiochemistryMicrobial CellPeer-reviewedJun 25, 2025

Knocking out histidine ammonia-lyase by using CRISPR-Cas9 abolishes histidine role in the bioenergetics and the life cycle of Trypanosoma cruzi.

Janaina De Freitas Nascimento, María Julia Barisón, Gabriela Torres Montanaro…·Ariel Mariano Silber

This study shows that knocking out histidine ammonia-lyase in Trypanosoma cruzi prevents histidine metabolism, affecting energy production and parasite life cycle.

1 citation

genetic perturbation / CRISPRhost-pathogen & immune response

𝕏 PostBluesky

Molecular BiologybioRxivPreprintSep 1, 2022

Global characterization of gene expression in the brain of starved immature R. prolixus

Jessica Coraiola Nevoa, José Manuel Latorre Estivalis, Fabiano Sviatopolk-Mirsky Pais…·Alessandra Aparecida Guarneri

The paper characterizes global gene expression in the brain of starved R. prolixus nymphs using RNASeq, identifying neuromodulatory genes and their expression patterns.

DOI 10.1101/2022.09.01.506236

bulk RNA-seqstatistical model

𝕏 PostBluesky

Molecular BiologyParasitologyPeer-reviewedNov 16, 2020

A Trypanosoma cruzi Zinc Finger protein that controls expression of epimastigote specific genes and affects metacyclogenesis

Thais Silva Tavares, Fernanda L. B. Mügge, Viviane Grazielle-Silva…·Santuza Maria Ribeiro Teixeira

The paper identifies a T. cruzi zinc finger protein, TcZC3H12, that regulates epimastigote gene expression and negatively affects metacyclogenesis.

15 citations

statistical modelgene regulatory network inference

𝕏 PostBluesky