MicrobiologybioRxivPreprint
Attenuated interferon signalling in alveolar epithelium limits resistance to Streptococcus pyogenes
Jeremy Wiyana, Declan L. Turner, Sahel Amoozadeh…·Rhiannon B. Werder
This study compares S. pyogenes infection responses in airway and alveolar epithelial cells, finding that alveolar cells show higher cell death and a pro-inflammatory response without cytokine secretion, and that IFN-β treatment reduces infection.
DOI 10.64898/2026.04.15.718576