Sunil Shrestha

This study enhances the maturity and functionality of liver organoids by combining 3D bioprinting with vascular progenitor cells and a pillar plate culture system.

This paper develops a cryopreservation technique for human brain organoids using a pillar plate platform, showing that smaller organoids and specific cryoprotective agents improve viability and differentiation.

This study evaluates developmental neurotoxicity using dynamic cerebral organoid cultures in a pillar/perfusion plate, showing methylmercury induces changes in morphology and gene expression under dynamic conditions but not static ones.

This paper develops a bioprinted liver organoid system for high-throughput hepatotoxicity assays, showing improved maturity, reproducibility, and regenerative capacity after drug exposure.

This paper develops a microarray 3D bioprinting method to generate human liver organoids on a pillar plate, enabling high-throughput, reproducible hepatotoxicity assays with improved efficiency and function.