NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Prolonged anesthesia alters brain synaptic architecture
Michael Wenzel, Alexander Leunig, Shuting Han…·Rafael Yuste
This study shows prolonged anesthesia in mice leads to cognitive impairment and altered synaptic turnover in the cortex, with increased synapse formation during anesthesia and loss afterward.
18 citations