Michael Wenzel

This study evaluates photopharmacology agents in human and mouse brain tissue to control epilepsy, finding that caged propofol suppresses epileptiform activity across species.

This study identifies region-specific spreading depolarization as a key factor in post-ictal behavioral abnormalities in epilepsy using mouse and human data.

The paper reports that common AAV transduction procedures can induce artefactual Ca2+ micro-waves in the hippocampus and provides an alternative method to avoid this issue.

This study shows prolonged anesthesia in mice leads to cognitive impairment and altered synaptic turnover in the cortex, with increased synapse formation during anesthesia and loss afterward.

The paper uses in-vivo two-photon calcium imaging to show that seizures begin as silent microseizures in neuronal ensembles before becoming detectable by LFP.

This study examines how medically-induced loss of consciousness affects cortical microstates and neuronal ensembles in mice and humans using imaging and electrophysiological data.

The paper investigates how inhibitory control affects the spread of focal ictal activity in a rodent model, showing that localized inhibition defects can lead to both classical and epileptic network propagation.