Author

Geoffrey L. Rogers

University of Southern CaliforniaORCID 0000-0002-9183-1269Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:CRISPR screen· 2 Research Focus:variant calling· 2 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Hsu-Yu CheniD· 3 shared Paula M. CannoniD· 3 shared Chun HuangiD· 2 shared Atishay MathuriD· 1 shared Chan-Hua Chang· 1 shared Eduardo SecléniD· 1 shared Elizabeth A. ShumaniD· 1 shared Heidy Morales· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Hsu-Yu ChenORCID

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Author profile →

3 papers

Recent·Most cited

Engineering B cells to Express Fully Customizable Antibodies with Enhanced Fc Functions

Chun Huang, Atishay Mathur, Chan-Hua Chang, Xiaoli Huang, Hsu-Yu Chen, Zachary Davis, Karla D. O'Dell, Elizabeth A. Shuman, Raymond W. Kung, Geoffrey L. Rogers, Paula M. Cannon

This study engineers B cells to express fully customizable antibodies with enhanced Fc functions through genome editing of the immunoglobulin Heavy chain locus.

Nature Communications · May 13, 2026Peer-reviewedImmunology

Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

Geoffrey L. Rogers, Chun Huang, Robert D.E. Clark, Eduardo Seclén, Hsu-Yu Chen, Paula M. Cannon

This study optimizes AAV6 transduction for ex vivo genome editing of human lymphocytes, achieving higher editing rates with reduced vector usage and toxicity.

Molecular Therapy — Methods & Clinical Development · Sep 10, 2021Peer-reviewedMolecular Biology

Homologous recombination-based genome editing by clade F AAVs is inefficient in the absence of a targeted DNA break

Geoffrey L. Rogers, Hsu-Yu Chen, Heidy Morales, Paula M. Cannon

The paper evaluates clade F AAVs for homologous recombination-based genome editing without DSBs, finding no detectable editing without ZFNs.

Molecular Therapy · Sep 9, 2019Peer-reviewedSynthetic Biology