Author

Kalappa Muniyappa

Indian Institute of Science BangaloreORCID 0000-0002-9192-9194Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anusha Singhal· 1 shared Kasi ManikandaniD· 1 shared Krishna Murari SinhaiD· 1 shared Kshitiza Mohan DhyaniiD· 1 shared Manoj ThakuriD· 1 shared Nisha Goyal· 1 shared Rahul SaginelaiD· 1 shared Shravanahalli C. SomashekaraiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMolecular Biology

Anusha Singhal

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Saccharomyces cerevisiae Rev7 promotes non-homologous end-joining by blocking Mre11 nuclease and Rad50's ATPase activities and homologous recombination

Sugith Babu Badugu, Kshitiza Mohan Dhyani, Manoj Thakur, Kalappa Muniyappa

This study shows that yeast Rev7 promotes non-homologous end-joining by inhibiting Mre11 nuclease and Rad50 ATPase activities, while blocking homologous recombination.

eLife · Dec 4, 2024Peer-reviewedMolecular Biology

Cyclic di-AMP regulates genome stability and drug resistance in Mycobacterium through RecA-dependent and -independent recombination

Sudhanshu Mudgal, Nisha Goyal, Kasi Manikandan, Rahul Saginela, Anusha Singhal, Soumyadeep Nandi, Kalappa Muniyappa, Krishna Murari Sinha

This study shows that cyclic di-AMP in Mycobacterium regulates genomic stability and drug resistance by modulating RecA-dependent and -independent DNA recombination and SOS response.

bioRxiv · May 13, 2024 · PreprintMolecular Biology

Dual targeting of Saccharomyces cerevisiae Pso2 to mitochondria and the nucleus, and its functional relevance in the repair of DNA interstrand crosslinks

Shravanahalli C. Somashekara, Kalappa Muniyappa

The paper investigates the dual localization of Pso2 in yeast mitochondria and nucleus and its role in DNA interstrand crosslink repair.

G3 Genes Genomes Genetics · Apr 28, 2022Peer-reviewedGenetics