Author

Alessio Mallozzi

Telethon Institute Of Genetics And MedicineORCID 0000-0002-9207-4589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:genome assembly· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Diego di BernardoiD· 2 shared Francesco RagazziniiD· 2 shared Virginia FuscoiD· 2 shared A. Arockia Jeyaprakash· 1 shared Arne Praznik· 1 shared Caitlin ReidiD· 1 shared Elisa PesentiiD· 1 shared Hiroshi MasumotoiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersSynthetic Biology

Diego di BernardoORCID

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3 papers

Recent·Most cited

The CRISPRaTOR: a biomolecular circuit for Automatic Gene Regulation in Mammalian Cells with CRISPR technology.

Alessio Mallozzi, Virginia Fusco, Francesco Ragazzini, Diego di Bernardo

The paper introduces CRISPRaTOR, a biomolecular circuit that maintains constant gene expression across varying conditions using CRISPR technology and synthetic domains.

ACS Synthetic Biology · Dec 2, 2024Peer-reviewedSynthetic Biology

A general strategy to engineer high-performance mammalian Whole-Cell Biosensors

Alessio Mallozzi, Virginia Fusco, Francesco Ragazzini, Arne Praznik, Roman Jerala, Diego di Bernardo

This paper introduces a method to design high-performance mammalian whole-cell biosensors by integrating synthetic biology and control engineering, resulting in a versatile biosensor named CASense.

bioRxiv · Feb 28, 2024 · PreprintSynthetic Biology

Analysis of Complex DNA Rearrangements During Early Stages of HAC Formation

Elisa Pesenti, Mikhail A. Liskovykh, Koei Okazaki, Alessio Mallozzi, Caitlin Reid, Maria Alba Abad, A. Arockia Jeyaprakash, Natalay Kouprina, Vladimir Larionov, Hiroshi Masumoto, William C. Earnshaw

This study tracks DNA rearrangements during HAC formation and finds that early stages involve DNA shredding and shuffling similar to chromothripsis.

ACS Synthetic Biology · Dec 8, 2020Peer-reviewedSynthetic Biology