Author
Wellcome Centre for Cell BiologyORCID 0000-0002-8816-1524Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Anjitha Gireesh, Maria Alba Abad, Ryu‐Suke Nozawa…·Arockia Jeyaprakash Arulanandam
This study reveals how the chromosomal passenger complex (CPC) interacts with nucleosomes to protect centromeric chromatin, showing its non-catalytic role in maintaining chromatin stability.
Kumiko Samejima, Johan Harmen Gibcus, Sameer Abraham…·William C. Earnshaw
In DT40 cells, condensins displace extrusive cohesin, bypass cohesive cohesin and stall against each other while extruding ~1-3 kb/sec, yielding irregular helical chromatids of consecutive loops.
Avinash V. Dharmadhikari, Maria Alba Abad, Reza Maroofian…·Universitat Autònoma de Barcelona. Departament de Medicina
The paper identifies SPOUT1/CENP-32 as a causative gene for SpADMiSS, linking its dysfunction to mitotic spindle defects and neurodevelopmental disorders.
Pragya Parashara, Bethan Medina‐Pritchard, Maria Alba Abad…·A. Arockia Jeyaprakash
The paper identifies PLK1-mediated phosphorylation of Mis18 and Mis18BP1 as essential for activating the Mis18 complex to ensure CENP-A loading and centromere inheritance.
Elisa Pesenti, Mikhail A. Liskovykh, Koei Okazaki…·William C. Earnshaw
This study tracks DNA rearrangements during HAC formation and finds that early stages involve DNA shredding and shuffling similar to chromothripsis.