Author
Wellcome Centre for Cell Biology
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
Avinash V. Dharmadhikari, Maria Alba Abad, Reza Maroofian…·Universitat Autònoma de Barcelona. Departament de Medicina
The paper identifies SPOUT1/CENP-32 as a causative gene for SpADMiSS, linking its dysfunction to mitotic spindle defects and neurodevelopmental disorders.
Thomas Kruse, Dimitriya Hristoforova Garvanska, Julia K. Varga…·Jakob Nilsson
The paper identifies conserved mechanisms by which PP2A-B55 substrates bind B55 through α-helices and develops a competitive inhibitor to study its function.
Pragya Parashara, Bethan Medina‐Pritchard, Maria Alba Abad…·A. Arockia Jeyaprakash
The paper identifies PLK1-mediated phosphorylation of Mis18 and Mis18BP1 as essential for activating the Mis18 complex to ensure CENP-A loading and centromere inheritance.
Sundar Ram Sankaranarayanan, Satya Dev Polisetty, Kuladeep Das…·Kaustuv Sanyal
The paper identifies a conserved arginine residue in the Dam1 complex subunit Dad2 that is essential for viability in yeast but less so in fungi with regional centromeres, suggesting functional plasticity in chromosome-microtubule coupling.
Desislava P. Staneva, Stefan M. Bresson, Tatsiana Auchynnikava…·Robin C. Allshire
The paper identifies the SPARC complex in Trypanosoma brucei, showing it defines RNAPII promoters and regulates transcription start site positioning and directionality.
Desislava P. Staneva, Roberta Carloni, Tatsiana Auchynnikava…·Robin C. Allshire
The paper identifies chromatin factors in Trypanosoma brucei and their association with transcription initiation and termination sites through proteomic and ChIP-seq analyses.
Elisa Pesenti, Mikhail A. Liskovykh, Koei Okazaki…·William C. Earnshaw
This study tracks DNA rearrangements during HAC formation and finds that early stages involve DNA shredding and shuffling similar to chromothripsis.