Author

Andrea Valls

Instituto de Salud Carlos IIIORCID 0000-0002-9211-4034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Amets SáenziD· 3 shared Cristina Ruiz‐RoldániD· 3 shared Adolfo López de MunainiD· 2 shared Agustín Martínez· 1 shared Ainhoa Vidal-GiliD· 1 shared Amaia EliceguiiD· 1 shared Ander MatheuiD· 1 shared Ane Otegui· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Amets SáenzORCID

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Author profile →

3 papers

Recent·Most cited

Comprehensive characterization of skeletal muscle remodeling in hSOD1G93A mice reveals limited functional impact of systemic FOXO1 inhibition

Ainhoa Vidal-Gil, Ignacio Azcue, María Levchuk, Amaia Elicegui, Oihane Pikatza‐Menoio, Maddalen Robles-Cantero, Ane Otegui, María Rodríguez-Hidalgo, Laura Moreno‐Martínez, Cristina Ruiz‐Roldán, Andrea Valls, Bahaa Daou, Mikel García-Puga, Itziar Vergara, Ander Matheu, , Sonia Alonso‐Martín

This study investigates the effects of systemic FOXO1 inhibition in hSOD1G93A mice, finding limited therapeutic benefit in modifying disease progression or muscle pathology.

bioRxiv · May 31, 2026 · PreprintNeuroscience

A New Approach to Modeling LGMDR1: Pyrvinium-Treated capn3b crispant Zebrafish

Cristina Ruiz‐Roldán, Andrea Valls, Jenita Immanuel, Flavia De Santis, Roberto Fernández‐Torrón, López de Munain Adolfo, Amets Sáenz

The paper develops a pharmacologically enhanced zebrafish model of LGMDR1 by treating capn3b mutants with pyrvinium, mimicking human gene expression patterns and highlighting Wnt pathway involvement.

bioRxiv · Nov 25, 2025 · PreprintMolecular Biology

The in-frame p.Lys254del-CAPN3 deletion is not sufficient to cause late-onset camptocormia in dominantly inherited calpainopathy

Andrea Valls, Gerardo Gutiérrez‐Gutiérrez, Agustín Martínez, Cristina Ruiz‐Roldán, Pilar Camaño, Adolfo López de Munaín, Amets Sáenz

The study shows that the p.Lys254del-CAPN3 mutation is not sufficient to cause late-onset camptocormia in dominant calpainopathy.

medRxiv · Jul 19, 2023 · PreprintGenetic & Genomic Medicine