Cancer BiologybioRxivPreprint
Toxicity Management in CAR T cell therapy for B-ALL: Mathematical modelling as a new avenue for improvement.
Shalla Hanson, David Robert Grimes, Jake P. Taylor-King…·Arturo Araujo
This paper develops a mathematical model to explore toxicity in CAR T cell therapy for B-ALL, finding that initial tumour burden is a stronger predictor of toxicity than CAR T cell dose.
DOI 10.1101/049908