Genomic landscape of drug response reveals novel mediators of anthelmintic resistance
Stephen R. Doyle, Roz Laing, David J. Bartley, Alison A. Morrison, Nancy E. Holroyd, Kirsty Maitland, Alistair Antonopoulos, Umer Naveed Chaudhry, Ilona Flis, Sue Howell, Jennifer McIntyre, John S. Gilleard, Andy Tait, Barbara K. Mable, Ray M. Kaplan, , James Anthony Cotton
The paper maps resistance loci for three anthelmintic classes in a parasitic nematode, identifies novel alleles for benzimidazoles and levamisole, and implicates cky-1 in ivermectin resistance.
bioRxiv · Nov 12, 2021 · PreprintGenomics