Jennifer McIntyre

This study assesses anthelmintic resistance in cattle nematodes using FECRT and molecular methods, finding high resistance allele frequencies and multidrug resistance in Scottish populations.

The paper generates a chromosome-scale genome assembly for Teladorsagia circumcincta and identifies genetic loci associated with drug resistance to improve anthelmintic resistance diagnostics.

The paper investigates the evolutionary dynamics of genes involved in heterochromatin functions in Drosophila, finding they evolve faster than Polycomb-based repressive chromatin genes.

The paper maps resistance loci for three anthelmintic classes in a parasitic nematode, identifies novel alleles for benzimidazoles and levamisole, and implicates cky-1 in ivermectin resistance.

This paper identifies gene expression changes associated with ivermectin resistance in parasitic nematodes through genetic crosses and RNA-seq, revealing upregulation of specific genes linked to neuronal plasticity and chloride homeostasis.