Author

Michał Śmiga

University of ManchesterORCID 0000-0002-9236-4236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Claire Morrisroe· 1 shared Katharine Z. CoyteiD· 1 shared Kirsten A. L. Y. LimiD· 1 shared Logan A. SauersiD· 1 shared Matthew R. HepworthiD· 1 shared Xiaotong Zhang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Claire Morrisroe

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1 paper

Recent·Most cited

Paired sequencing of IgA-bound bacteria reveals widespread associations between adaptive immunity and gut microbiome gene expression.

Logan A. Sauers, Kirsten A. L. Y. Lim, Xiaotong Zhang, Claire Morrisroe, Michał Śmiga, Matthew R. Hepworth, Katharine Z. Coyte

The paper introduces PIg-seq to study IgA-bound bacteria and finds widespread transcriptional responses, including changes in conjugation genes and prophages, linking IgA to horizontal gene transfer.

bioRxiv · Oct 5, 2026 · PreprintMicrobiology