Author

Yoshito Hirata

University of TsukubaORCID 0000-0002-9245-2543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:dimensionality reduction· 2 Assay:Hi-C· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Arisa OdaiD· 1 shared Chie MotonoiD· 1 shared Eric J. LangiD· 1 shared Hiroki SugishitaiD· 1 shared Huu HoangiD· 1 shared Isao T. TokudaiD· 1 shared Kazuyuki AiharaiD· 1 shared Keisuke ToyamaiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Arisa OdaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsScientific ReportsPeer-reviewedJul 11, 2022

Imputation-free reconstructions of three-dimensional chromosome architectures in human diploid single-cells using allele-specified contacts

Yoshito Hirata, Arisa Oda, Chie Motono…·Kunihiro Ohta

This paper introduces an algorithm to reconstruct 3D chromosome structures in single human diploid cells using allele-specific SNVs without imputation, achieving resolutions of 40-kb to 1-Mb.

7 citations

humanHi-C

Developmental BiologybioRxivPreprintMay 20, 2021

Changes of chromosomal architecture before establishment of chromosome territories revealed by recurrence plot reconstruction

Yuki Kitanishi, Hiroki Sugishita, Yukiko Gotoh, Yoshito Hirata

The paper uses scHi-C data and the RPR method to analyze changes in chromosomal architecture during early embryogenesis, revealing intermingling of paternal/maternal chromosomes and Rabl-like polarization.

2 citations

mouseHi-C

NeurosciencePLoS Computational BiologyPeer-reviewedJan 1, 2019

Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons

Huu Hoang, Eric J. Lang, Yoshito Hirata…·Nicolas Schweighofer

This study models how electrical coupling between inferior olive neurons affects firing dimensionality and chaos, supporting the hypothesis that coupling controls learning efficiency in the cerebellum.

19 citations

statistical model