Isao T. Tokuda

The paper develops a computational model of the wheat circadian oscillator to explain the altered timing of ELF3 expression compared to Arabidopsis.

The paper develops conceptual models of circadian entrainment using global optimization to explain phenotypic features like phase response curves and seasonal variability.

The paper shows that weak coupling between feedback loops in circadian clocks leads to dissociated gene expression dynamics at the single-cell level.

This study models how electrical coupling between inferior olive neurons affects firing dimensionality and chaos, supporting the hypothesis that coupling controls learning efficiency in the cerebellum.

The paper examines single-cell circadian rhythms in Arabidopsis seedlings, revealing robust oscillations and spatial waves of gene expression that coordinate clock activity across the plant.

This study shows that SIK3 regulates circadian rhythms in mice by destabilizing PER2 protein through phosphorylation.