Isabelle Dupanloup

The population history of northeastern Siberia since the Pleistocene

This paper analyzes ancient genomes from northeastern Siberia to reveal complex population migrations and admixture events over the past 40,000 years.

Relaxed selection during a recent human expansion

The paper examines genomic diversity in French Canadians to show that range expansion led to relaxed selection, increasing the frequency of deleterious mutations in colonizing populations.

Genetic surfing in human populations: from genes to genomes

The paper examines genetic surfing in human populations, showing an increase in recessive mutation load with distance from Africa during human expansion.

Distance from Sub-Saharan Africa Predicts Mutational Load in Diverse Human Genomes

The paper examines how distance from Sub-Saharan Africa correlates with mutational load in diverse human populations, finding that populations further from Africa have higher mutation loads due to recessive mutations.

Inference of evolutionary forces acting on human biological pathways

The paper introduces a new statistical method, 2DNS, to detect selection acting on human biological pathways by analyzing genetic diversity and evolutionary constraints.