Author

Elias Gbeha

Ontario Institute for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:variant effect prediction· 2 Assay:bulk RNA-seq· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alan HodgkinsoniD· 3 shared Philip AwadallaiD· 3 shared Elodie Hip-Ki· 2 shared Vanessa BruatiD· 2 shared Youssef IdaghdouriD· 2 shared Adrien Foucal· 1 shared Alexandre GouyiD· 1 shared Audrey SmargiassiiD· 1 shared

Activity by Year

2014-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersGenomics

Alan HodgkinsonORCID

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Author profile →

3 papers

Recent·Most cited

Genomic and Environmental Contributions to Chronic Diseases in Urban Populations

Marie-Julie Favé, Fabien Claude Lamaze, David M. Soave, Alan Hodgkinson, Héloïse Gauvin, Vanessa Bruat, Jean‐Christophe Grenier, Elias Gbeha, Kimberly Skead, Audrey Smargiassi, Markey Johnson, Youssef Idaghdour, Philip Awadalla

The paper investigates how environmental factors, particularly air pollution, interact with genetic variation to influence gene expression and chronic disease traits in an urban population.

Nature Communications · Feb 20, 2018Peer-reviewedGenomics

Relaxed selection during a recent human expansion

Stephan Peischl, Isabelle Dupanloup, Adrien Foucal, Michèle Jomphe, Vanessa Bruat, Jean-Cristophe Grenier, Alexandre Gouy, Elias Gbeha, Lars Bosshard, Elodie Hip-Ki, Mawussé Agbessi, Alan Hodgkinson, Hélène Vézina, Philip Awadalla, Laurent Excoffier

The paper examines genomic diversity in French Canadians to show that range expansion led to relaxed selection, increasing the frequency of deleterious mutations in colonizing populations.

Genetics · Feb 1, 2018Peer-reviewedGenomics

Recombination impacts damaging and disease mutation accumulation in human populations

Julie Hussin, Alan Hodgkinson, Youssef Idaghdour, Jean-Christophe Grenier, Jean-Philippe Goulet, Elias Gbeha, Elodie Hip-Ki, Philip Awadalla

The paper shows that recombination rate influences the distribution of deleterious variants across the human genome, with low recombination regions enriched for disease-associated mutations.

bioRxiv · Sep 10, 2014Evolutionary Biology