Alain Frigon

Spinal rotational dynamics orchestrate locomotor recovery

This study shows that spinal motor populations use rotational dynamics in a low-dimensional neural manifold for locomotion, which persists after spinal cord injury and suggests an intrinsic spinal attractor mechanism.

EFFECTS OF SPINAL TRANSECTION AND LOCOMOTOR SPEED ON MUSCLE SYNERGIES OF THE CAT HINDLIMB

This study examines how spinal transection and locomotor speed affect muscle synergies in cat hindlimbs, finding that while specific synergies change, the overall organization remains consistent.

Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection

The paper uses a computational model to simulate and predict changes in locomotion phase durations after a spinal hemisection in cats, comparing results with experimental data.

ROLE OF FORELIMB MORPHOLOGY IN MUSCLE SENSORIMOTOR FUNCTIONS DURING LOCOMOTION IN THE CAT

This study examines how forelimb muscle morphology in cats influences sensorimotor functions during locomotion, finding that muscle structure affects force and sensory signals related to lateral stability and turning.

Operation regimes of spinal circuits controlling locomotion and role of supraspinal drives and sensory feedback

This study develops a computational model of spinal locomotor circuits in cats to show that the spinal network operates in different regimes depending on locomotor speed and supraspinal input.

Changes in intra- and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats

This study examines changes in reflex pathways from forelimb cutaneous afferents after thoracic spinal cord injuries in cats, showing reduced hindlimb reflex responses and altered coordination during locomotion.

Forelimb movements contribute to hindlimb cutaneous reflexes during locomotion in cats

This study investigates how forelimb movements affect hindlimb cutaneous reflexes during locomotion in cats, showing that forelimb movement influences the modulation of these reflexes, especially long-latency responses.

Changes in intra- and interlimb reflexes from hindlimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats

This study examines how spinal cord injuries affect cutaneous reflexes and interlimb coordination during locomotion in cats, finding reduced mid- and long-latency reflex responses correlate with impaired balance and coordination.

Neuromechanical strategies for obstacle negotiation during overground locomotion following an incomplete spinal cord injury in adult cats

This study examines how adult cats negotiate obstacles after spinal cord injury, finding improved clearance over time with changes in muscle activation and weight distribution.

Spinal sensorimotor circuits play a prominent role in hindlimb locomotor recovery after staggered thoracic lateral hemisections but cannot restore posture and interlimb coordination during quadrupedal locomotion in adult cats

Cutaneous inputs from perineal region facilitates and modulates spinal locomotor activity and reduces cutaneous reflexes from the foot in spinal cats

This study shows that perineal mechanical stimulation modulates spinal locomotor activity and reduces cutaneous reflexes in spinal cats, suggesting it excites central pattern-generating circuits rather than increasing reflex gain.

On the organization of the locomotor CPG: insights from split-belt locomotion and mathematical modeling

This paper investigates the organization of locomotor CPG circuits by testing a hypothesis about state-dependent changes in rhythm generator operation using experimental and mathematical modeling approaches.