Author

Xiaobo B Han

Tohoku Institute of TechnologyORCID 0000-0002-9285-4796Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Ikuro SuzukiiD· 2 shared Naoki MatsudaiD· 2 shared Eikan MishimaiD· 1 shared Kanako Sato· 1 shared Kuniyasu NiizumaiD· 1 shared Makoto Yamanaka· 1 shared Mikako Shibata· 1 shared Nami Nagafuku· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ikuro SuzukiORCID

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3 papers

Recent·Most cited

Development of a novel microphysiological system for neurotoxicity prediction using human iPSC-derived neurons with morphological deep learning

Xiaobo B Han, Naoki Matsuda, Makoto Yamanaka, Ikuro Suzuki

The paper develops a microphysiological system using human iPSC-derived neurons and morphological deep learning to predict neurotoxicity from drugs, showing effectiveness in detecting synaptic degeneration and chemotherapy-induced neuropathy.

Toxics · Nov 11, 2024Peer-reviewedPharmacology & Toxicology

Large-area electrical imaging having single neuron resolution using 236,880 electrodes CMOS-MEA technology

Ikuro Suzuki, Naoki Matsuda, Xiaobo B Han, Shuhei Noji, Mikako Shibata, Nami Nagafuku, Y. Ishibashi

The paper introduces a high-resolution CMOS-MEA technology for single-cell neural activity analysis and demonstrates its application in studying brain circuits and drug responses.

bioRxiv · Nov 9, 2022 · PreprintNeuroscience

The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation

Sherif Rashad, Xiaobo B Han, Kanako Sato, Eikan Mishima, Takaaki Abe, Teiji Tominaga, Kuniyasu Niizuma

This study investigates how Alkbh1 affects tRNA cleavage and tiRNA generation under stress in rat cells, showing stress-specific impacts and differential tRNA cleavage.

RNA Biology · Jun 10, 2020Peer-reviewedMolecular Biology