Author

Kristina Shkirkova

University of Southern CaliforniaORCID 0000-0002-9288-4258Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Caleb E. FinchiD· 2 shared Constantinos SioutasiD· 2 shared Max Andrew ThorwaldiD· 2 shared William J. MackiD· 2 shared Albina Ibreyeva· 1 shared Alexandra N. DemetriouiD· 1 shared Angela M. Tang-TaniD· 1 shared Ararat ChakhoyaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersNeuroscience

Caleb E. FinchORCID

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2 papers

Recent·Most cited

Induction of ferroptotic and amyloidogenic signatures linked to Alzheimers disease by chemically distinct air pollutants

Kristina Shkirkova, Naomi S. Sta Maria, Herbert Anson, Yashar Aghaei, Mohammad Mahdi Badami, Ararat Chakhoyan, José A. Godoy-Lugo, Claire S Chung, Salma Durra, Angela M. Tang-Tan, Lifu Zhao, Alexandra N. Demetriou, Manuel Morales, Sindhu Daggupati, Isabella Bent, , Max Andrew Thorwald

This study shows that metal-rich air pollutants induce ferroptosis and amyloidogenic pathways linked to Alzheimer's disease through shared transcriptional and oxidative mechanisms.

Redox Biology · Sep 15, 2026Peer-reviewedNeuroscience

Single cell profiling reveals GSM-15606 attenuates air pollution-induced inflammation and preserves hippocampal neurogenesis

Mohammad Shariq, Wanqing Pan, Xiran Chen, Wang Xiang, Jose Godoy Lugo, Lei Peng, Jonathan N. Levi, Albina Ibreyeva, Kristina Shkirkova, Wynnie Nguyen, Constantinos Sioutas, William J. Mack, Caleb E. Finch, Max Andrew Thorwald, Michael A. Bonaguidi

The paper uses single-cell RNA sequencing to show GSM-15606 reduces inflammation and preserves neurogenesis in the hippocampus of mice exposed to air pollution.

bioRxiv · Jan 30, 2026 · PreprintNeuroscience