Author

Kai Shing

Massachusetts General HospitalORCID 0000-0002-9321-6382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adel BoudiiD· 3 shared Ellen SappiD· 3 shared Kimberly B. Kegel-GleasoniD· 3 shared Marian DiFigliaiD· 3 shared Connor Seeley· 2 shared Neil Aronin M. DiD· 2 shared Sophia Liu· 2 shared Ana Rita BatistaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersNeuroscience

Adel BoudiORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 15, 2025

Early reduction and impaired targeting of myelin-associated glycoprotein to myelin membranes in Huntington disease

Adel Boudi, Ellen Sapp, Yvonnie Y Li…·Xueyi Li

This study identifies early reduction and impaired trafficking of myelin-associated glycoprotein in Huntington disease mouse models, contributing to white matter degradation.

DOI 10.1101/2025.10.15.682629

mouseexperimental assay

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NeurosciencebioRxivPreprintJan 6, 2025

Intrastriatal delivery of a zinc finger protein targeting the mutant HTT gene by AAV9 obviates lipid phenotypes in brain and plasma of zQ175DN HD mice

Andrew Iwanowicz, Adel Boudi, Connor Seeley…·Kimberly B. Kegel-Gleason

The paper shows that reducing mutant HTT with a zinc finger protein in HD mice prevents lipid changes in brain and plasma.

DOI 10.1101/2025.01.06.630918

mouseproteomics

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NeuroscienceNeurobiology of DiseasePeer-reviewedSep 28, 2023

Early whole-body mutant huntingtin lowering averts changes in proteins and lipids important for synapse function and white matter maintenance in the LacQ140 mouse model

Kai Shing, Ellen Sapp, Adel Boudi…·Kimberly B. Kegel-Gleason

15 citations

mouseproteomics

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