Cancer BiologybioRxivPreprint
IL-1R1 Blockade Enhances CD40 Agonist-Mediated Immune Responses but Fails to Increase Efficacy or Mitigate Hepatotoxicity in Pancreatic Cancer
Akash R. Boda, Irfan N. Bandey, Saikat Chowdhury…·Manisha Singh
This study investigates the effect of IL-1R1 blockade on CD40 agonist therapy in PDAC, finding it does not improve efficacy and worsens liver toxicity.
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