Fabiola Valdivia-Francia

In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging

The paper uses in vivo single-cell ribosome profiling to study translational changes in mouse epidermal stem cells during aging, finding cell-type-specific translational reprogramming in aged stem cells.

Regulation of mRNA polyadenylation governs mammalian body plan formation in gastruloids

This study identifies mRNA deadenylation as a key mechanism regulating body plan formation in mouse gastruloids by affecting mesoderm and endoderm differentiation.

The alternative initiation factor eIF2A regulates 40S subunit turnover in ribosome-associated quality control

This study identifies eIF2A's role in ribosome-associated quality control by showing it antagonizes USP10-dependent 40S subunit rescue, affecting turnover under stress.

In vivo single-cell CRISPR screening for microproteins identifies a critical ribosomal component

The paper uses in vivo single-cell CRISPR screening in mouse epidermis to identify a microprotein critical for ribosome function and cell proliferation.