Author

Yuri Rafael de Oliveira Silva

Lehigh UniversityORCID 0000-0002-9339-0727Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew Santiago‐FrangosiD· 1 shared Arav Nangia· 1 shared Balwina KoopaliD· 1 shared Daniel ZhitnitskyiD· 1 shared Dia Zheng· 1 shared Grayson BarnesiD· 1 shared Jack P. K. BravoiD· 1 shared John D. HelmanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Andrew Santiago‐FrangosORCID

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2 papers

Recent·Most cited

The bacterial antiphage protein Tiamat is an ATPase and DNase whose homologs are found across the tree of life

Shirley Yuan, Yuri Rafael de Oliveira Silva, Balwina Koopal, Vinh Dang, Arav Nangia, Jack P. K. Bravo, Andrew Santiago‐Frangos

This study identifies Tiamat as an ATPase and DNase in bacteria and shows its homologs are widespread across eukaryotes, with some acquiring non-defense roles.

bioRxiv · Oct 1, 2026 · PreprintBiochemistry

Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ

Yuri Rafael de Oliveira Silva, Grayson Barnes, Dia Zheng, Daniel Zhitnitsky, Samuel J. Geathers, Stephen C. Peters, Veronika A. Szalai, John D. Helmann, Oriana S. Fisher

This study identifies a Cu(II) exchange mechanism between YcnI and YcnJ in B. subtilis, showing their roles in copper acquisition and regulation under copper limitation.

Journal of Biological Chemistry · Jul 15, 2025Peer-reviewedBiochemistry