Beshay N. M. Zordoky

Integrated Omics Approach to Delineate the Mechanisms of Doxorubicin-Induced Cardiotoxicity

This study uses multi-omics analysis to identify molecular pathways and temporal changes in doxorubicin-induced cardiotoxicity in mice, revealing potential biomarkers for cardioprotection.

Divergent Immediate and Delayed Effects of Juvenile Exposure to Doxorubicin on the Thymus in C57BL/6 Mice

This study examines the immediate and delayed effects of juvenile doxorubicin exposure on thymic immune cell populations and gene expression in mice, revealing thymic atrophy and immunosenescence.

Inhibition of Cyp1a Protects Mice against Anthracycline Cardiomyopathy

This study shows that inhibiting Cyp1a protects mice from anthracycline-induced cardiomyopathy by reducing cardiac dysfunction and altering gene expression related to mitophagy and inflammation.