Christina D. Camell

The paper identifies age-dependent senescent endothelial cells in adipose tissue using snRNA-Seq and finds ion channel genes as predictive biomarkers.

This study shows that GDF3 promotes inflammation in aged adipose tissue macrophages via SMAD2/3 signaling and chromatin changes, offering a therapeutic target for age-related inflammation.

This study identifies nerve-associated macrophages (NAMs) as regulators of adipose homeostasis and inflammation during aging, showing their depletion accelerates inflammaging and impairs lipolysis.

This study examines the immediate and delayed effects of juvenile doxorubicin exposure on thymic immune cell populations and gene expression in mice, revealing thymic atrophy and immunosenescence.

This study characterizes epigenetic aging in human classical monocytes, identifying age-associated DNA methylation changes and their links to gene expression and disease associations.