Accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features
Ahmed A. Abbas, Khyati Raghunath Chandratre, Yunpeng Gao, Jiapei Yuan, Michael Q. Zhang, Ram Shankar Mani
The paper introduces ChIPr, a model predicting cohesin-mediated chromatin interactions from 2D features, showing strong correlation with ChIA-PET data and capturing cell-type-dependent loops.
Genome biology · Jan 12, 2024Peer-reviewedGenomics