Qiuyu Lian

AAB-seq identifies antigen-binding antibodies with affinity information from single-cell BCR sequencing in immunized mice.

This paper develops a xeno-free human iPSC-derived prostate organoid platform that enables multilineage differentiation and genetic manipulation for studying prostate biology and disease.

VeloTrace unifies RNA velocity and trajectory inference using NeuralODEs, improving accuracy and coherence in single-cell transcriptomic analysis.

The paper identifies shared proliferation acceleration and heterogeneous transcriptional changes during B-lymphoid and neutrophil/monocyte lineage restriction from CD34+ cord blood cells.

TIST integrates spatial transcriptomics data with histopathological images to improve spatial cluster identification and gene expression analysis.

This paper introduces GMM-Demux, a method to identify and remove multiplets in scRNA-seq data, showing improved accuracy and error reduction.

CITE-sort improves cell type classification in CITE-seq by addressing artificial cell types caused by multiplets, achieving better clustering performance than existing methods.

The paper identifies recurrently deregulated lncRNAs in HCC and PVTT samples, linking them to metastasis and prognosis using multi-omics data.