Jing Tang

Seasonal photoperiod cycling reduces inter-individual variability in mu-opioid receptor density in rats

This study shows that seasonal photoperiod cycling reduces inter-individual variability in mu-opioid receptor density in rats compared to constant photoperiod conditions.

Predicting Pre-treatment Resistance or Post-treatment Effect? A Systematic Benchmarking of Single-Cell Drug Response Models

This study benchmarks single-cell drug response models across 26 datasets, showing performance varies with dataset type, imbalance, and model design, with scDEAL showing competitive results.

Mechanisms that regulate the C1-C2B mutual inhibition controls functional switch of UNC-13

This study identifies a mechanism by which UNC-13 in C. elegans regulates synaptic vesicle exocytosis through domain interactions and functional switches.

Natural Variation in Arabidopsis Cvi-0 Accession Uncovers Regulation of Guard Cell CO2 Signaling by MPK12

The paper identifies a single amino acid substitution in MPK12 causing ozone hypersensitivity and stomatal CO2-insensitivity in Arabidopsis, revealing MPK12's role as an inhibitor of HT1 in guard cell CO2 signaling.

Methods for High-Throughput Drug Combination Screening and Synergy Scoring

The paper develops an experimental-computational pipeline for high-throughput drug combination screening and synergy scoring in cancer cells.

Recurrently deregulated lncRNAs associated with HCC tumorigenesis and metastasis revealed by genomic, epigenomic and transcriptomic profiling in paired primary tumor and PVTT samples

The paper identifies recurrently deregulated lncRNAs in HCC and PVTT samples, linking them to metastasis and prognosis using multi-omics data.