Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein
Lynette Nel, Katja Thaysen, Denisa Jamecna, Esben Olesen, Maria Szomek, Julia Langer, Kelly May Frain, Doris Höglinger, Daniel Wüstner, Bjørn Panyella Pedersen
This study investigates the lipid binding properties of the yeast NCR1/NPC2 system using crystal structures and binding assays, revealing its ability to bind multiple lipids beyond sterols.
Life Science Alliance · Oct 25, 2024Peer-reviewedBiophysics