Author

Jakob Christensen

Aarhus UniversityORCID 0000-0002-9385-6435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Anders Dupont BørglumiD· 2 shared Bjarni Jóhann VilhjálmssoniD· 2 shared DAVID MICHAEL HOUGAARDiD· 2 shared Jakob GroveiD· 2 shared Jonas Bybjerg‐GrauholmiD· 2 shared Julie Werenberg DreieriD· 2 shared Merete NordentoftiD· 2 shared Ole N MorsiD· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Anders Dupont BørglumORCID

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2 papers

Recent·Most cited

Accounting for age-of-onset and family history improves power in genome-wide association studies

Emil M. Pedersen, Esben Agerbo, Oleguer Plana‐Ripoll, Jakob Grove, Julie Werenberg Dreier, Katherine Louise Musliner, Marie Bækvad‐Hansen, Georgios I. Athanasiadis, Andrew Joseph Schork, Jonas Bybjerg‐Grauholm, DAVID MICHAEL HOUGAARD, Thomas Mears Werge, Merete Nordentoft, Ole N Mors, Søren Dalsgaard, , Bjarni Jóhann Vilhjálmsson

This paper introduces LT-FH++, a method that improves GWAS power by incorporating age-of-onset and family history, showing increased significant associations in psychiatric disorders and mortality data.

The American Journal of Human Genetics · Feb 8, 2022Peer-reviewedBioinformatics

Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

Line Skotte, João Fadista, Jonas Bybjerg‐Grauholm, Vivek Appadurai, Michael S. Hildebrand, Thomas Folkmann Hansen, Karina Banasik, Jakob Grove, Clara Albiñana, Frank Geller, Carmen Flores, Bjarni Jóhann Vilhjálmsson, Matthew Coleman, John A. Damiano, Rosemary Burgess, , Bjarke Feenstra

This study identifies seven new genetic loci associated with febrile seizures, linking them to fever response and neuronal excitability genes, and suggests potential clinical applications of polygenic risk scores.

Brain · Jul 9, 2021Peer-reviewedGenetic & Genomic Medicine