Author

Claudio Bussi

The Francis Crick InstituteORCID 0000-0002-9396-9042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ambrosius P. SnijdersiD· 1 shared Callan L BuechsenschuetziD· 1 shared Darryl HaywardiD· 1 shared Dorota Gibbins· 1 shared Elizabeth FisheriD· 1 shared Emmanuel DeauiD· 1 shared Eva Lana‐ElolaiD· 1 shared Helen R. FlynniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Ambrosius P. SnijdersORCID

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1 paper

Recent·Most cited

Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A

Eva Lana‐Elola, Rifdat Aoidi, Miriam Llorian, Dorota Gibbins, Callan L Buechsenschuetz, Claudio Bussi, Helen R. Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie Haugsten Hansen, Darryl Hayward, Ok‐Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, , Victor L. J. Tybulewicz

The paper shows increased DYRK1A dosage causes mitochondrial dysfunction and congenital heart defects in Down syndrome, which can be mitigated by a DYRK1A inhibitor.

bioRxiv · Sep 18, 2023 · PreprintDevelopmental Biology