Author
The Francis Crick InstituteORCID 0000-0002-8462-2741Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Oscar Atkins, Miu Shing Hung, Ok‐Ryul Song…·Dinis Pedro Calado
This study identifies relapse-founding cancer persister cells in follicular lymphoma using a mouse model and shows their transcriptional program is conserved in humans, with potential therapeutic targets identified.
N. Bishara Marzook, Ok‐Ryul Song, Lotta Baumgärtel…·Adam Sateriale
The paper uses a CRISPR-Cas9 screen to identify host genes critical for Cryptosporidium survival, revealing a metabolic dependency on host cholesterol biosynthesis that can be targeted for treatment.
Francesca Torelli, Simon Butterworth, Eloise J. Lockyer…·Moritz Treeck
The paper identifies GRA12 as a critical secreted virulence factor in Toxoplasma gondii that functions across different parasite strains and mouse species.
Eva Lana‐Elola, Rifdat Aoidi, Miriam Llorian…·Victor L. J. Tybulewicz
The paper shows increased DYRK1A dosage causes mitochondrial dysfunction and congenital heart defects in Down syndrome, which can be mitigated by a DYRK1A inhibitor.