Eric J. Delpire

Calmodulin mutation N54I causes autosomal dominant CPVT in mice

This paper shows that a single copy of the N54I calmodulin mutation in mice causes CPVT-like arrhythmias, demonstrating the functional dominance of mutant calmodulin.

An Alport variant illuminates the bioactivity of the collagen IV α565- α121 scaffold in Bowman's capsule.

The paper investigates the bioactivity of the collagen IV α565-α121 scaffold in Bowman's capsule by analyzing the effects of a Z-appendage variant in Col4a5.

Kidney kallikrein-1 contributes to cleavage of gamma-ENaC in vivo

This study shows that kidney kallikrein-1 contributes to gamma-ENaC cleavage but is not essential for overall ENaC function or electrolyte balance.

NRBP1 and TSC22D proteins impact distal convoluted tubule physiology through modulation of the WNK pathway

This study shows NRBP1 and TSC22D proteins modulate WNK signaling in the kidney's distal convoluted tubule, affecting Na+ reabsorption through NCC phosphorylation.

Inhibiting CRF Projections from the Central Amygdala to Lateral Hypothalamus and Amygdala Deletion of CRF Alters Binge-Like Ethanol Drinking in a Sex-Dependent Manner

This study shows that inhibiting CRF projections from the central amygdala to the lateral hypothalamus reduces binge-like ethanol drinking in male, but not female, mice.