Johannes Loffing

This study shows high-salt diets increase urinary cortisol and decrease plasma FGF23, revealing a novel endocrine interaction with implications for bone, kidney, and cardiovascular health.

This study shows that chronic FGF23 elevation causes kidney inflammation via sustained ERK signaling, which is reduced by cFGF23 gene therapy.

This study shows that Nup133 deficiency in zebrafish causes kidney cysts and glomerular damage, mimicking human nephrotic syndrome features.