PhysiologybioRxivPreprint
Chronically elevated FGF23 drives sustained renal ERK signaling and inflammatory transcriptional programs mitigated by cFGF23 gene therapy
Adrián Salas-Bastos, Claire Bardet, Klaudia Kopper…·Ganesh Pathare
This study shows that chronic FGF23 elevation causes kidney inflammation via sustained ERK signaling, which is reduced by cFGF23 gene therapy.
3 citations