Author

Shikha Gupta

Harvard UniversityORCID 0000-0002-9416-1360Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ananthan SadagopaniD· 1 shared Bingchen LiiD· 1 shared Eddy SaadiD· 1 shared Jiao LiiD· 1 shared Prateek KhannaiD· 1 shared Prathyusha KondaiD· 1 shared Qingru XuiD· 1 shared Ramaprasad SrinivasaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ananthan SadagopanORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 11, 2025

Dual Inhibition of CDK4/6 and mTORC1 Establishes a Preclinical Strategy for Translocation Renal Cell Carcinoma

Shikha Gupta, Prateek Khanna, Eddy Saad…·Srinivas R. Viswanathan

This study identifies CDK4/6 and mTORC1 pathway activation in tRCC and shows that their dual inhibition synergistically suppresses tRCC cell growth in vitro and xenografts in vivo.

DOI 10.1101/2025.07.11.663903

humanbulk RNA-seq

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