Hui Chen

Empirical Bayes Estimation of Sample-Specific Correlation Networks for Cross-Sectional and Longitudinal Omics Data

PRISM estimates sample-specific correlation networks for cross-sectional and longitudinal omics data, improving accuracy and uncertainty quantification over existing methods.

Spatially ordered zygotic genome activation fulfills embryo quality control

The paper shows that properly patterned zygotic genome activation (ZGA) is required for normal development and that embryos have a quality control system to detect and respond to mispatterned ZGA.